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42722 3-Hydroxy-3-methylbutyric acid, 96%

CAS Number
625-08-1
Synonyms
beta-Hydroxyisovaleric acid

Stock No. Size Price ($) Quantity Availability
42722-09 10g 31.60
42722-18 50g 86.30
42722-30 250g 347.00
42722-A1 1kg 1222.00
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3-Hydroxy-3-methylbutyric acid, 96%

MDL
MFCD00059081

Chemical Properties

Formula
C5H10O3
Formula Weight
118.13
Form
Liquid
Boiling Point
128°/7mm
Flash Point
113°(235°F)
Density
1.1
Refractive Index
1.4408
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water and ethanol.

Applications

3-Hydroxy-3-methylbutyric acid is a useful biochemical for synthesis and proteomics research. It is used as an indicator of biotin deficiency. Further, it is used to increase muscle mass and decrease muscle breakdown. In addition to this, it is involved in the protein synthesis.

Notes

Moisture sensitive. Incompatible with strong oxidizing agents.

Literature References

Dhar, A.; Dhar, K.; Rosazza, J. P. N. Purification and characterization of a Galactomyces reessii hydratase that converts 3-methylcrotonic acid to 3-hydroxy-3-methylbutyric acid. J. Ind. Microbiol. Biotechnol. 2002, 28 (2), 81-87.

Gogerty, D. S.; Bobik, T. A. Formation of Isobutene from 3-Hydroxy-3-Methylbutyrate by Diphosphomevalonate Decarboxylase. Appl. Environ. Microbiol. 2010, 76 (24), 8004-8010.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1743952
Harmonized Tariff Code
2918.19
TSCA
No

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