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Palladium(II) acetate is a catalyst of choice for a wide variety of reactions such as vinylation, Wacker process, Buchwald-Hartwig amination, carbonylation, oxidation, rearrangement of dienes (e.g., Cope rearrangement), C-C bond formation, reductive amination, etc. Precursor to Pd(0), other Pd(II) compounds of catalytic significance, and Pd nanowires.
Zhang, S.; Shi, L.; Ding, Y. Theoretical Analysis of the Mechanism of Palladium(II) Acetate-Catalyzed Oxidative Heck Coupling of Electron-Deficient Arenes with Alkenes: Effects of the Pyridine-Type Ancillary Ligand and Origins of the meta-Regioselectivity. J. Am. Chem. Soc. 2011, 133 (50), 20218-20229.
Albert, J.; Granell, J.; Tavera, R. On the Mechanism of the Cyclopalladation Reaction of Benzyl-benzylidene-Amine with Palladium(II)acetate in Acetic acid. J. Organomet. Chem. 2003, 667, 192-196.
Hazard Statements: H290-H318
May be corrosive to metals. Causes serious eye damage.
Precautionary Statements: P280-P305+P351+P338-P310-P390
Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Absorb spillage to prevent material damage.