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43144 5-Sulfosalicylic acid dihydrate, ACS, 99+%

CAS Number
5965-83-3
Synonyms
2-Hydroxy-5-sulfobenzoic acid dihydrate

Stock No. Size Price ($) Quantity Availability
43144-14 25g 21.80
43144-22 100g 48.70
43144-36 500g 142.00
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5-Sulfosalicylic acid dihydrate, ACS, 99+%

MDL
MFCD00007508
EINECS
202-555-6

Chemical Properties

Formula
C7H6O6S•2H2O
Formula Weight
254.22 (218.19anhy)
Form
Powder
Melting point
103-112°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in water, alcohol, ether and polar solvents.

Grade Specifications

Maximum level of impurities: Insoluble matter 0.02%, Residue after ignition 0.1%, Cl 0.001%, HOC6H4COOH 0.04%, SO4 0.02%, Pb 0.002%, Fe 0.001%

Applications

Reagent for precipitation of proteins5-Sulfosalicylic acid dihydrate is used as a metal scavenger and it forms proton-transfer dye complexes with diazo compounds such as 4-(phenyldiazenyl)aniline. It is employed as a preparative measure for removing proteins prior to chromatographic analysis. It plays a vital role in reducing and fixation of proteins in agarose and polyacrylamide gels. It acts as a surfactant and lubricating grease additive. It is also used in urine tests to determine urine protein content. Further, it acts as an intermediate in the synthesis of active pharmaceutical ingredients like doxycycline and methacycline. In addition to this, it is used as a spray reagent for the detection of amino acids on thin layer chromatography (TLC) plates and as a doping agent for polyaniline.

Notes

Light sensitive. Incompatible with strong oxidizing agents and strong bases.

Literature References

Cui, M.; Lin, H.; Wang, X.; Cao, L.; Sui, J. 5-sulfosalicylic Acid Dihydrate-Based Pretreatment for the Modification of Enzyme-Linked Immunoassay of Fluoroquinolones in Fishery Products. J. Immunoassay Immunochem. 2015, 36 (5), 517-531.

Jin, W.; Huang, P.; Wu, F.; Ma, L. H. Ultrasensitive colorimetric assay of cadmium ion based on silver nanoparticles functionalized with 5-sulfosalicylic acid for wide practical applications. Analyst 2015, 140 (10), 3507-3513.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H314

Harmful if swallowed. Causes severe skin burns and eye damage.

Precautionary Statements: P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,8964
Beilstein
650741
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2918.29
TSCA
Yes
RTECS
VO6500000

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