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43244 Dimethylsuberimidate dihydrochloride

CAS Number
34490-86-3
Synonyms

Stock No. Size Price ($) Quantity Availability
43244-04 2g 39.70
43244-09 10g 154.00
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Dimethylsuberimidate dihydrochloride

MDL
MFCD00012574
EINECS
252-060-4

Chemical Properties

Formula
C10H20N2O2•2HCl
Formula Weight
273.20
Form
Crystalline
Melting point
213-214°
Storage & Sensitivity
Moisture Sensitive. Ambient temperatures.
Solubility
Soluble in water.

Applications

Dimethylsuberimidate dihydrochloride is used as a homobifunctional cross-linking reagent for amino groups. It is also used for the modification of tyrosinase to produce biocatalytic enzymatic flow-through detectors. It serves as a cross-linker for preparation of collagen-calcium phosphate composites. Further, it is used in the treatment of avian myeloblastosis virus.

Notes

Moisture sensitive. Incompatible with oxidizing agents, strong bases and halogens.

Literature References

King, M. J.; Jepson, M. A.; Guest, A.; Mushens, R. Detection of hereditary pyropoikilocytosis by the eosin-5-maleimide (EMA)-binding test is attributable to a marked reduction in EMA-reactive transmembrane proteins. Int. J. Lab. Hematol. 2011, 33 (2), 205-211.

Suzuki, C.; Yun, C. S.; Umeda, T.; Terabayashi, T.; Watanabe, K.; Yamane, H.; Nojiri, H. Oligomerization and DNA-binding capacity of Pmr, a histone-like protein H1 (H-NS) family protein encoded on IncP-7 carbazole-degradative plasmid pCAR1. Biosci. Biotechnol. Biochem. 2011, 75 (4), 711-717.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2917.19
TSCA
Yes

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