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43492 5-Methylcytosine, 97%

CAS Number
554-01-8
Synonyms

Stock No. Size Price ($) Quantity Availability
43492-MC 100mg 87.70
43492-ME 500mg 336.00
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5-Methylcytosine, 97%

MDL
MFCD00233537
EINECS
209-058-3

Chemical Properties

Formula
C5H7N3O
Formula Weight
125.13
Form
Crystalline
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

5-Methylcytosine is used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes. It is also employed in the production of 4-amino-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-imidazole-1-carbaldehyde.

Notes

Moisture sensitive. Incompatible with acids,oxidizing agents, acid chloride, acid anhydrides and peroxide.

Literature References

Hashimoto, H.; Zhang, X.; Vertino, P. M.; Cheng, X. The Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine Oxidations. J. Biol. Chem. 2015, 290 (34), 20723-20733.

Moen, E. L.; Mariani, C. J.; Zullow, H.; Jeff-Eke, M.; Litwin, E.; Nikitas, J. N.; Godley, L. A. New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine. Immunol. Rev. 2015, 263 (1), 36-49.

Other References

Merck
14,6050
Harmonized Tariff Code
2933.59
TSCA
No
RTECS
UW7362350

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