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1-Hydroxyethylidenebis(phosphonic acid) acts as human protein tyrosine phosphatase inhibitor. It is also useful for photographic applications. It finds application to strengthen bone, osteoporosis treatment and to treat Paget's disease of bone. In addition, it is used in corrosion inhibition in circulating cool water systems, oil fields and low-pressure boilers with electric power, the chemical industry, metallurgy and fertilizers. It is also utilized for formulating reverse osmosis and thermal desalination anti-scaling agents. Furthermore, it is used in detergents, water treatment, cosmetics and pharmaceuticals.
Lin, X. Z.; Yang, Z. Z.; He, L. N.; Yuan, Z. Y. Mesoporous zirconium phosphonates as efficient catalysts for chemical CO2 fixation. Green Chem. 2015, 17 (2), 795-798.
Semenov, V. V.; Zolotareva, N. V.; Petrov, B. I.; Baranov, E. V.; Titova, V. I.; Varlamova, L. D.; Geiger, E. Y.; Korolenko, I. D.; Dabakhova, E. V. Preparation of amorphous water-soluble complexes of biometals with (1-hydroxyethylidene) diphosphonic acid, 2-aminoethanol, and 2-amino-2-(hydroxymethyl) propane-1, 3-diol. Russ. J. Gen. Chem. 2015, 85 (5), 1116-1124.
Hazard Statements: H314-H335
Causes severe skin burns and eye damage. May cause respiratory irritation.
Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant