Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

43928 N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal™ bottles

CAS Number
25561-30-2
Synonyms

Stock No. Size Price ($) Quantity Availability
43928-06 5g 36.80
43928-14 25g 107.00
Add to Cart Add to Quote Request View Item

N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal™ bottles

MDL
MFCD00008269
EINECS
247-103-9

Chemical Properties

Formula
C8H18F3NOSi2
Formula Weight
257.40
Form
Liquid
Melting point
-10°
Boiling Point
145-147°
Flash Point
23°(73°F)
Density
0.97
Refractive Index
1.3840
Storage & Sensitivity
Keep Cold. Moisture Sensitive. Store under Nitrogen.
Solubility
Soluble in water (hydrolyses), chloroform and hexane.

Applications

N,O-Bis(trimethylsilyl)trifluoroacetamide is used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. It is silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions. It is also used as DAT inhibitor and a SLC6A2 inhibitor. It is routinely used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides.

Notes

Store at 4°C. Keep cool and dry in tightly closed container. Protect from heat and moisture. Store away from oxidizing agents.

Literature References

Ali Shareef,; Craig J Parnis,; Michael J Angove,; John D Wells,; Bruce B Johnson.Suitability of N,O-bis(trimethylsilyl)trifluoroacetamide and N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide as derivatization reagents for the determination of the estrogens estrone and 17α-ethinylestradiol by gas chromatography-mass spectrometry. Journal of Chromatography A. 2004 , 1026 (1-2),295-300.

GHS Hazard and Precautionary Statements

Hazard Statements: H226-H314-H318

Flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3607620
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2931.90
TSCA
Yes

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware