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2,2-Diphenyl-1-picrylhydrazyl is used as a sensitive colorimetric free radical scavenger. It serves as a general antioxidant detector. It is utilized to monitor chemical reactions involving radicals as well as a standard of the position and intensity of electron paramagnetic resonance signals. Further, it is employed in the quantitative determination of aliphatic and aromatic thiols by indirect spectroscopy and for photometric determination of tocopherol.
Nakanishi, I.; Ohkubo, K.; Imai, K.; Kamibayashi, M.; Yoshihashi, Y.; Matsumoto, K.; Fukuhara, K.; Terada, K.; Itoh, S.; Ozawa, T. Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by beta-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media. Chem. Commun. 2015, 51, 8311-8314.
Volkov, V. A.; Misin, V. M. Kinetics of reactions of antioxidants from some food and medicinal plants with the stable radical 2,2-diphenyl-1-picrylhydrazyl. Kinet. Catal. 2015, 56 (1), 43-48.
Hazard Statements: H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Precautionary Statements: P284-P261-P280g-P342+P311a-P363-P501a
Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Wash contaminated clothing before reuse. Dispose of contents/container in accordance with local/regional/national/international regulations.