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Methyl (S)-(+)-3-hydroxy-2-methylpropionate is used as a starting material for the synthesis of dictyostatin, discodermolide and spongidepsin.
Lee, P.; Raj, S. M.; Zhou, S.; Ashok, S.; Edwardraja, S.; Park, S. 3-hydroxyisobutyrate dehydrogenase-I from Pseudomonas denitrificans ATCC 13867 degrades 3-hydroxypropionic acid. Biotechnol. Bioprocess Eng. 2015, 19 (1), 1-7.
Subrao, M.; Potukuchi, D. M.; Ramachandra, G. S.; Bhagavath, P.; Bhat, S. G.; Maddasani, S. Novel biphenyl-substituted 1, 2, 4-oxadiazole ferroelectric liquid crystals: synthesis and characterization. Beilstein J. Org. Chem. 2015, 11 (1), 233-241.
Hazard Statements: H227-H315-H319-H335
Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P210u-P261-P280a-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.