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44605 Hydrogen chloride, nominally 2.5M in ethanol

CAS Number
7647-01-0
Synonyms

Stock No. Size Price ($) Quantity Availability
44605-AK 250ml 86.20
44605-K2 1L 230.00
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Hydrogen chloride, nominally 2.5M in ethanol

MDL
MFCD00011324
EINECS
231-595-7

Chemical Properties

Formula
HCl
Formula Weight
36.46
Form
Liquid
Storage & Sensitivity
Ambient temperatures.
Solubility
Miscible with water at room temperature. Also miscible with methanol, ethanol and ether.

Applications

Hydrogen chloride, 2.5M. in ethanol is used in the manufacturing of pharmaceuticals to get a hydrochloride salt. For example, ranitidine base is converted to ranitidine hydrochloride, which is used as anti ulcerative drug.

Notes

Molarity range: 2.0 to 3.0.

Hydrogen chloride is corrosive when it comes in contact with water found in body tissue.

Literature References

Hartman, M.; Svoboda, K.; Pohorely, M.; Syc, M.; Skoblia, S.; Chen, P. C. Reaction of Hydrogen Chloride Gas with Sodium Carbonate and Its Deep Removal in a Fixed-Bed Reactor. Ind. Eng. Chem. Res. 2014, 53 (49), 19145-19158.

Islam, M. A.; Rahman, M. M. Dissolution kinetics of colloidal manganese dioxide in aqueous hydrochloric acid at 298 K. J. Phys. Chem. C 2015, <89/span> (4), 706-709.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H290-H314-H332-H335

Highly flammable liquid and vapour. May be corrosive to metals. Causes severe skin burns and eye damage. Harmful if inhaled. May cause respiratory irritation.

Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P390-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Absorb spillage to prevent material damage. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2806.10
TSCA
Yes

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