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45782 Polyvinylpyrrolidone-iodine complex

CAS Number
25655-41-8
Synonyms

Stock No. Size Price ($) Quantity Availability
45782-18 50g 37.90
45782-30 250g 157.00
45782-A1 1kg 520.00
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Polyvinylpyrrolidone-iodine complex

MDL
MFCD00084483

Chemical Properties

Formula
(C6H9NO)n.xI
Form
Powder
Melting point
300° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water, ethyl alcohol, isopropyl alcohol, polyethylene glycol and glycerol. Insoluble in chloroform, carbon tetrachloride, hexane, acetone and petroleum ether.

Applications

Polyvinylpyrrolidone-iodine complex is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine side chains. It is utilized to study microbial decontamination of human donor eyes as well as inactivation of infectious hematopoietic necrosis virus. It is also used as a carbon nanotube coating agent to enhance water solubility. It serves as a topical antiseptic in surgery, as an aerosol for skin and mucous membrane infections and is used to prevent infection in wounds.

Notes

Incompatible with oxidizing agents.

Literature References

Zhao, Y.; Yan, J.; Xia, Y.; Zhang, F.; Gu, N. Enhanced Osteogenesis of Polyvinylpyrrolidone-Iodine as a Sterilizing Agent for Preservation of Allografts. J Biomater Tissue Eng 2015, 5 (6), 465-471.

Jiang, Y.; Chen, L.; Zhang, S.; Tong, T.; Zhang, W.; Liu, W.; Xu, G.; Tuan, R. S.; Heng, B. C.; Crawford, R.; Xiao, Y.; Ouyang, H. W. Incorporation of bioactive polyvinylpyrrolidone-iodine within bilayered collagen scaffolds enhances the differentiation and subchondral osteogenesis of mesenchymal stem cells. Acta Biomater. 2013, 9 (9), 8089-8098.

Other References

Merck
14,7698
Harmonized Tariff Code
3905.99
TSCA
Yes
RTECS
TR1579600

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