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45847 Hydroxypropyl methylcellulose, 28-30% methoxyl, 7-12% hydroxypropyl, viscosity (2% aq. soln., 20°C) 7500-14000 mPa.s

CAS Number
9004-65-3
Synonyms
Methocel
HPMC

Stock No. Size Price ($) Quantity Availability
45847-22 100g 30.30
45847-36 500g 96.40
45847-A4 2.5kg 363.00
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Hydroxypropyl methylcellulose, 28-30% methoxyl, 7-12% hydroxypropyl, viscosity (2% aq. soln., 20°C) 7500-14000 mPa.s

MDL
MFCD00131360

Chemical Properties

Form
Powder
Storage & Sensitivity
Ambient temperatures.
Solubility
Miscible with water, ethanol, ether, acetone and organic solvents.

Applications

Hydroxypropyl methylcellulose is used as an ophthalmic lubricant, an emulsifier and a thickening and suspending agent. It is widely used as an excipient in pharmaceutical formulations. It also acts as a food additive. Its eye drops are known as artificial tears, which are used to relieve eye dryness and soreness. It finds applications in various fields as tile adhesives, gypsum products, cosmetics, cement renders, contact lenses, detergents and cleaners.

Notes

Incompatible with strong oxidizing agents, bleaching powder, fluorine and nitric acid.

Literature References

Pattnaik, S.; Swain, K.; Rao, J. V.; Varun, T.; Prusty, K. B.; Subudhi, S. K. Aceclofenac nanocrystals for improved dissolution: influence of polymeric stabilizers. RSC Adv. 2015, 5 (112), 91960-91965.

Bitterlich, A.; Laabs, C.; Krautstrunk, I.; Dengler, M.; Juhnke, M.; Grandeury, A.; Bunjes, H.; Kwade, A. Process parameter dependent growth phenomena of naproxen nanosuspension manufactured by wet media milling. Eur. J. Pharm. Biopharm. 2015, 92, 171-179.

Qiu, S.; Li, M. Effects of coformers on phase transformation and release profiles of carbamazepine cocrystals in hydroxypropyl methylcellulose based matrix tablets. Int. J. Pharm. 2015, 479 (1), 118-128.

Other References

Merck
14,4842
Harmonized Tariff Code
3912.39
TSCA
Yes
RTECS
NF9125000

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