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46384 6-Maleimidohexanoic acid

CAS Number
55750-53-3
Synonyms
6-Maleimidocaproic acid
MCA

Stock No. Size Price ($) Quantity Availability
46384-06 5g 36.30
46384-14 25g 112.00
46384-22 100g 449.00
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6-Maleimidohexanoic acid

MDL
MFCD00043140

Chemical Properties

Formula
C10H13NO4
Formula Weight
211.22
Form
Powder
Storage & Sensitivity
Keep Cold. Moisture Sensitive.
Solubility
Soluble in water, methanol, ethanol, dimethyl sulfoxide. Insoluble in ether.

Applications

6-Maleimidohexanoic acid is used as a probe for introducing maleimides groups into biomolecules and active pharmaceutical ingredients. Further, it is used with N-hydroxysuccinimide ester as a bifunctional cross-linking reagent. In addition to this, it acts as a probe for thiol groups in membrane proteins.

Notes

Moisture sensitive. Incompatible with strong oxidizing agents, strong acids and strong bases and strong reducing agents

Literature References

Duval, A.; Lange, H.; Lawoko, M.; Crestini, C. Reversible crosslinking of lignin via the furan-maleimide Diels-Alder reaction. Green Chem. 2015, 17 (11), 4991-5000.

Fang, J.; Ye, S. H.; Wang, J.; Zhao, T.; Mo, X.; Wagner, W. R. Thiol Click Modification of Cyclic Disulfide Containing Biodegradable Polyurethane Urea Elastomers. Biomacromolecules 2015, 16 (5), 1622-1633.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2925.19
TSCA
No

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