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Reagent for protection of amino groups as benzylsulfonamides which can be cleaved reductively, e.g. Na/NH3, Raney Ni/H2: J. Am. Chem. Soc., 79, 639, 645 (1957), or by photolysis: Tetrahedron Lett., 1029 (1979)./n
Alcohols can also be protected, e.g. in the presence of 2,6-lutidine, as benzylsulfonates which can be cleaved with NaNH2 in DMF: Bull. Chem. Soc. Jpn., 59, 1587 (1986)./n
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P201-P280i-P304+P340-P405-P501a
Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.