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147-24-0 - Diphenhydramine hydrochloride, 99% - A10136 - Alfa Aesar

A10136 Diphenhydramine hydrochloride, 99%

CAS Number
147-24-0
Synonyms

Size Price ($) Quantity Availability
50g 26.90
250g 84.40
1000g 291.00
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Diphenhydramine hydrochloride, 99%

MDL
MFCD00012479
EINECS
205-687-2

Chemical Properties

Formula
(C6H5)2CHOCH2CH2N(CH3)2•HCl
Formula Weight
291.82
Melting point
168-169°
Sensitivity
Light Sensitive
Solubility
Soluble in water, dimethyl sulfoxide, dimethylformamide, methanol and ethanol.

Applications

A histamine H1 receptor antagonistDiphenhydramine hydrochloride acts as a sodium channel blocker. It is used as a histamine H1-receptor antagonist. Further, it is used as a sedative, hypnotic, antiemetic, antitussive and pruritus. It is employed in the treatment of allergic conditions. In addition to this, it is used as an active ingredient in common cold preparations.

Notes

Incompatible with strong oxidizing agents, strong acids and alkalis.

Literature References

Miao, C.; Zhang, A.; Xu, Y.; Chen, S.; Ma, F.; Huang, C.; Jia, N. An ultrasensitive electrochemiluminescence sensor for detecting diphenhydramine hydrochloride based on l-cysteine-functionalized multiwalled carbon nanotubes/gold nanoparticles nanocomposites. Sens. Actuators, B 2015, 213, 5-11.

Jengathe, S. P.; Dhondge, S. S.; Paliwal, L. J.; Tangde, V. M.; Mondal, S. Effect of sodium chloride and myo-inositol on diphenhydramine hydrochloride drug in aqueous solution at different temperatures: Volumetric and acoustic approach. J. Chem. Thermodyn. 2015, 87, 78-87.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2922.19
TSCA
No
RTECS
KR7000000

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