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A10138 1,4-Dithioerythritol, 98+%

CAS Number
6892-68-8
Synonyms
Cleland's Reagent DTE
erythro-1,4-Dimercapto-2,3-butanediol

Stock No. Size Price ($) Quantity Availability
A10138-06 5g 110.00
A10138-14 25g 423.00
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1,4-Dithioerythritol, 98+%

MDL
MFCD00063750
EINECS
229-998-8

Chemical Properties

Formula
C4H10O2S2
Formula Weight
154.25
Melting point
82-84°
Storage & Sensitivity
Keep Cold. Air Sensitive. Store under Nitrogen.
Solubility
Soluble in water (15.4 mg/ml), and methanol.

Applications

Reagent for maintaining -SH groups in the reduced state, quantitatively reduces disulfides.

Notes

Air Sensitive, store away form air. Keep the container tightly sealed. Store away from reducing agent. Store under dry inert gas.

Literature References

Morgane Riou; David Stroebel; J Michael Edwardson; Pierre Paoletti. An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors. Plosone. 2012, 7 (4), 35134 .

Yang-Rae Kim et. al. Highly sensitive gold nanoparticle-based colorimetric sensing of mercury(II) through simple ligand exchange reaction in aqueous media. ACS Applied Materials & Interfaces. 2010, 2 (1), 292-295.

Protective agent for preventing oxidation of thiol groups and reagent for reduction of disulfide groups in proteins: Biochemistry, 3, 480 (1964); 11, 2939 (1972); J. Biol. Chem., 243, 716 (1968); compare 1,4-Dithio-DL-threitol, A15797.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335-H500

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May form combustible dust concentrations in air

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1719756
Hazard Class
9
Packing Group
III
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
KF2410000

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