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6892-68-8 - 1,4-Dithioerythritol, 99% - Cleland's Reagent DTE - erythro-1,4-Dimercapto-2,3-butanediol - A10138 - Alfa Aesar

A10138 1,4-Dithioerythritol, 99%

CAS Number
6892-68-8
Synonyms
Cleland's Reagent DTE
erythro-1,4-Dimercapto-2,3-butanediol

Size Price ($) Quantity Availability
1g 39.04
5g 116.39
25g 378.50
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1,4-Dithioerythritol, 99%

MDL
MFCD00063750
EINECS
229-998-8

Chemical Properties

Formula
C4H10O2S2
Formula Weight
154.25
Melting point
82-84°
Sensitivity
Air Sensitive
Solubility
Soluble in water (15.4 mg/ml), and methanol.

Applications

Reagent for maintaining -SH groups in the reduced state, quantitatively reduces disulfides.

Notes

Air Sensitive, store away form air. Keep the container tightly sealed. Store away from reducing agent. Store under dry inert gas.

Literature References

Morgane Riou; David Stroebel; J Michael Edwardson; Pierre Paoletti. An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors. Plosone. 2012, 7 (4), 35134 .

Yang-Rae Kim et. al. Highly sensitive gold nanoparticle-based colorimetric sensing of mercury(II) through simple ligand exchange reaction in aqueous media. ACS Applied Materials & Interfaces. 2010, 2 (1), 292-295.

Protective agent for preventing oxidation of thiol groups and reagent for reduction of disulfide groups in proteins: Biochemistry, 3, 480 (1964); 11, 2939 (1972); J. Biol. Chem., 243, 716 (1968); compare 1,4-Dithio-DL-threitol, A15797.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1719756
Hazard Class
9
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
KF2410000

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