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tert-Butylacetyl chloride is used an acyl chloride compound for proteomics research. It is also used as intermediate for important acylation reagents agrochemical and pharmaceutical.
August H. Homeyer; Frank C. Whitmore; V. H. Wallingford. Preparation of tert-Butylacetic Acid and its Derivatives. J. Am. Chem. Soc. 1933, 55,(10), 4209-4214.
August H. Homeyer; Frank C. Whitmore; V. H. Wallingford. Conformations and internal rotation barriers in tert-butylacetaldehyde and tert-butylacetyl halides. J. Phys. Chem. 1980, 84,(14), 1785-1789.
Hazard Statements: H225-H314-H318
Highly flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.