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tert-Butylacetyl chloride is used an acyl chloride compound for proteomics research. It is also used as intermediate for important acylation reagents agrochemical and pharmaceutical.
August H. Homeyer; Frank C. Whitmore; V. H. Wallingford. Preparation of tert-Butylacetic Acid and its Derivatives. J. Am. Chem. Soc. 1933, 55,(10), 4209-4214.
August H. Homeyer; Frank C. Whitmore; V. H. Wallingford. Conformations and internal rotation barriers in tert-butylacetaldehyde and tert-butylacetyl halides. J. Phys. Chem. 1980, 84,(14), 1785-1789.
Hazard Statements: H225-H314-H335
Highly flammable liquid and vapour. Causes severe skin burns and eye damage. May cause respiratory irritation.
Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant