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2-Acetylbenzoic acid is used as a component of hair dyes. It is used as an intermediate for pharmaceutical, cosmetics, agrochemical and food industries.
Jacob Finkelstein; Thomas Williams; Voldemar Toome; Samuel Traiman. Ring-chain tautomers of 6-substituted 2-acetylbenzoic acids. J. Org. Chem. 1967, 32 (10), 3229-3230.
A. J. Dobson and R. E. Gerkin. 2-Acetylbenzoic Acid: Phthalide Form. Acta Cryst. 1996, C52 3078-3081.
Exists in equilibrium with 3-hydroxy-3-methylphthalide, precursor of 3-methylenephthalidyl (MPID) derivatives of amino acids. Deprotection can be effected with hydrazine hydrate: Synthesis, 43 (1977).
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P280g-P305+P351+P338
Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.