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3-Methyl-2-pyrazolin-5-one is used in the preparation of spirocyclic [indole-3,4'-pyrano[2,3-c]pyrazole] by reacting with isatins and malonitrile in the presence of sodium bromide as electrolyte.
Vereshchagin, A. N.; Elinson, M. N.; Dorofeeva, E. O.; Nasybullin, R. F.; Bushmarinov, I. S.; Goloveshkin, A. S.; Egorov, M. P. Electrocatalytic cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles: one-pot simple fast and efficient way to substituted spirocyclopropylpyrazolones. Electrochim. Acta 2015, 165, 116-121.
Wang, H. X.; Wu, L. L.; Wang, Y. M.; Zhou, Z. H. Organocatalyzed asymmetric tandem Michael-cyclization reaction of 4-benzylidene-3-methylpyrazol-5-ones and malononitrile: stereocontrolled construction of pyrano[2,3-c]pyrazole scaffold. RSC Adv. 2015, 5 (53), 42836-42842.