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2-Ketoglutaric acid is used as an intermediate in the krebs cycle catalyzed by glutamate dehydrogenase enzyme on glutamate. It is also used in dietary supplements to improve protein synthesis.
T. Garcia-Rodriguez; A.M. GuTierrez-Navarro; R. Garcia; J.Perez Silva. Indole acetic acid production by Rhizobium: Effect of 2-ketoglutaric acid. Soil Biol. Biochem. 1982, 14,(2), 153-155.
F. Rocchiccioli; J. P. Leroux; and P. H. Cartier. Microdetermination of 2-ketoglutaric acid in plasma and cerebrospinal fluid by capillary gas chromatography mass spectrometry; application to pediatrics. Biological Mass Spectrometry. 1984, 11,(1), 24-28.
Hazard Statements: H318
Causes serious eye damage.
Precautionary Statements: P280-P305+P351+P338-P310
Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.