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100-48-1 - 4-Cyanopyridine, 98% - Isonicotinonitrile - Pyridine-4-carbonitrile - A10286 - Alfa Aesar

A10286 4-Cyanopyridine, 98%

CAS Number
100-48-1
Synonyms
Isonicotinonitrile
Pyridine-4-carbonitrile

Size Price ($) Quantity Availability
10g 14.94
100g 17.55
500g 57.44
2500g 242.05
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4-Cyanopyridine, 98%

MDL
MFCD00006417
EINECS
202-856-2

Chemical Properties

Formula
C6H4N2
Formula Weight
104.11
Melting point
76-80°
Boiling Point
194-196°
Flash Point
88°(190°F)
Solubility
Soluble in water.

Applications

4-Cyanopyridine is used as an intermediate in organic synthesis and pharmaceutical substances like isonicotinylhydrazide, which is used in the treatment of tuberculosis. It is used as a precursor for the preparation of isonicotinic acid and 4-diemthylaminopyridine (DMAP). It is involved in the synthesis of 6-methyl-2-pyridin-4-yl-pyrimidin-4-ylamine by reacting with acetonitrile.

Notes

Incompatible with strong acids, strong bases and strong oxidizing agents.

Literature References

Naika, R. M.; Kumar, B.; Prasad, S.; Chetty, A. A.; Asthana, A. Catalytic ligand exchange reaction between hexacyanoferrate(II) and 4-cyanopyridine applied to trace kinetic analysis of palladium(II). Microchem. J. 2015, 122, 82-88.

Naik, R. M.; Asthana, A.; Yadav, S. B. S. Comparative study of the catalytic effect of Ag(I) and Hg(II) on the exchange of cyanide by 4-cyanopyridine in hexacyanoferrate(II): a kinetic approach. J. Iran. Chem. Soc. 2015, 12 (3), 519-528.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H319

Harmful if swallowed. Causes serious eye irritation.

Precautionary Statements: P280f-P305+P351+P338

Wear protective clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Beilstein
107712
Harmonized Tariff Code
2933.39
TSCA
Yes

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