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A10286 4-Cyanopyridine, 98%

CAS Number
100-48-1
Synonyms
Isonicotinonitrile
Pyridine-4-carbonitrile

Stock No. Size Price ($) Quantity Availability
A10286-09 10g 15.60
A10286-22 100g 19.50
A10286-36 500g 74.00
A10286-0E 2500g 252.00
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4-Cyanopyridine, 98%

MDL
MFCD00006417
EINECS
202-856-2

Chemical Properties

Formula
C6H4N2
Formula Weight
104.11
Melting point
76-80°
Boiling Point
194-196°
Flash Point
88°(190°F)
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

4-Cyanopyridine is used as an intermediate in organic synthesis and pharmaceutical substances like isonicotinylhydrazide, which is used in the treatment of tuberculosis. It is used as a precursor for the preparation of isonicotinic acid and 4-diemthylaminopyridine (DMAP). It is involved in the synthesis of 6-methyl-2-pyridin-4-yl-pyrimidin-4-ylamine by reacting with acetonitrile.

Notes

Incompatible with strong acids, strong bases and strong oxidizing agents.

Literature References

Naika, R. M.; Kumar, B.; Prasad, S.; Chetty, A. A.; Asthana, A. Catalytic ligand exchange reaction between hexacyanoferrate(II) and 4-cyanopyridine applied to trace kinetic analysis of palladium(II). Microchem. J. 2015, 122, 82-88.

Naik, R. M.; Asthana, A.; Yadav, S. B. S. Comparative study of the catalytic effect of Ag(I) and Hg(II) on the exchange of cyanide by 4-cyanopyridine in hexacyanoferrate(II): a kinetic approach. J. Iran. Chem. Soc. 2015, 12 (3), 519-528.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H302-H312-H315-H319-H332-H335

Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. Harmful if inhaled. May cause respiratory irritation.

Precautionary Statements: P210-P235-P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
107712
Harmonized Tariff Code
2933.39
TSCA
Yes

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