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Methyl chloroacetate is used as a solvent and chemical intermediate. It acts as a precursor in the preparation of (carboxymethyl) trimethylammonium chloride esters. Further, it is used in the preparation of octakis-(carbethoxymethoxy)calixarene. It is employed as an extraction solvent during the separation of neutral compounds. In addition to this, it is used in the synthesis of dimethyl carbonate.
Hu, K.; Zhao, D.; Wu, G.; Ma, J. Polyesters derived from bio-based eugenol and 10-undecenoic acid: synthesis, characterization, and structure-property relationships. RSC Adv. 2015, 5 (105), 85996-86005.
Wang, X. F.; Hai, X.; Shu, Y.; Chen, X. W.; Wang, J. H. A novel cross-linked co-polymeric ionic liquid as a potential adsorbent for highly efficient adsorption of curcuminoids. Anal. Methods 2015, 7 (22), 9529-9534.
Hazard Statements: H226-H301-H310+H330-H315-H317-H318-H335
Flammable liquid and vapour. Toxic if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye damage. May cause respiratory irritation.
Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P262-P264b-P270-P271-P272-P280-P284-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P330-P333+P313-P363-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Do not get in eyes, on skin, or on clothing. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant