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A10335 Salicylanilide, 98%

CAS Number
87-17-2
Synonyms
2-Hydroxybenzanilide

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Salicylanilide, 98%

MDL
MFCD00002212
EINECS
201-727-8

Chemical Properties

Formula
C13H11NO2
Formula Weight
213.24
Melting point
136-138°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

It is employed as a drug used to treat rheumatoid arthritis and has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. It is used mainly in medicated soaps.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Rohit Sharma, et al. Isocitrate lyase: a potential target for anti-tubercular drugs.Recent Pat Inflamm Allergy Drug Discov.,2013,7(2), 114-23.

Robert G. Freeman, MD; John M. Knox, MD. The Action Spectrum of Photocontact Dermatitis Caused by Halogenated Salicylanilide and Related Compounds.Arch Dermatol.,1968,97(2), 130-136.

Ghazi IM, et al. Antibacterial effect and toxicity of synthesized salicylanilide derivatives.Zentralbl Mikrobiol.,1986,141(3), 225-32.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,8330
Harmonized Tariff Code
2924.29
TSCA
Yes

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