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A10337 4-Methylumbelliferone, 97%

CAS Number
90-33-5
Synonyms
7-Hydroxy-4-methylcoumarin
Hymecromone

Stock No. Size Price ($) Quantity Availability
A10337-18 50g 27.50
A10337-30 250g 98.60
A10337-0B 1000g 294.00
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4-Methylumbelliferone, 97%

MDL
MFCD00006866
EINECS
201-986-7

Chemical Properties

Formula
C10H8O3
Formula Weight
176.17
Melting point
186-191°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in alcohol. Insoluble in cold water. Soluble in acetic acid, alkali and ammonium hydroxide. Slightly soluble in hot water, chloroform and diethyl ether.

Applications

4-Methylumbelliferone is used in the determination of nitric acid and as a standard for fluorometric determination of enzyme activity. It is also used in bile therapy.

Notes

Store in a cool place. Incompatible with strong bases and strong oxidizing agents.

Literature References

Standard for fluorimetric determination of enzyme activity: Anal. Biochem., 54, 40; 55, 85 (1973).

/n

Franco, P. G.; Perez, M. J.; Aranda, C.; Adamo, A.; Silvestroff, L. Improving arylsulfatase activity determination in dried blood spots: Screening and diagnostic approaches for Maroteaux-Lamy syndrome (MPS VI). Clin. Chim. Acta 2015, 446, 86-92.

Kłucinska, K.; Jurczakowski, R.; Maksymiuk, K.; Michalska, A. Ultrasensitive 4-methylumbelliferone fluorimetric determination of water contents in aprotic solvents. Talanta 2015, 132, 392-397.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335-H500

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May form combustible dust concentrations in air

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,4854
Beilstein
142217
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2932.20
TSCA
Yes
RTECS
GN7000000

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