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A10363 2,4-Dichloro-6-methylpyrimidine, 98%

CAS Number
5424-21-5
Synonyms

Stock No. Size Price ($) Quantity Availability
A10363-14 25g 64.00
A10363-22 100g 187.00
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2,4-Dichloro-6-methylpyrimidine, 98%

MDL
MFCD00006064
EINECS
226-563-4

Chemical Properties

Formula
C5H4Cl2N2
Formula Weight
163.01
Melting point
44-47°
Boiling Point
219°
Flash Point
>110°(230°F)
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in Chloroform, Ether, Ethyl Acetate and Toluene. Insoluble in water.

Applications

2,4-Dichloro-6-methylpyrimidine is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine.

Notes

Store away from oxidizing agents and bases. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Eliud Hernández, et al. Novel inhibitors of Rac1 in metastatic breast cancer.P R Health Sci J.,2010,29(4), 348-56.

Caroline Hadad, et al. 4-Arylvinyl-2,6-di(pyridin-2-yl)pyrimidines: synthesis and optical properties.J Org Chem.,2011,76(10), 3837-45.

Wei Zhang. Fluorous synthesis of disubstituted pyrimidines.Org Lett.,2003,5(7), 1011-3.

GHS Hazard and Precautionary Statements

Hazard Statements: H314

Causes severe skin burns and eye damage.

Precautionary Statements: P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
114295
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2933.59
TSCA
Yes

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