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624-49-7 - Dimethyl fumarate, 99% - Fumaric acid dimethyl ester - A10402 - Alfa Aesar

A10402 Dimethyl fumarate, 99%

CAS Number
624-49-7
Synonyms
Fumaric acid dimethyl ester

Size Price ($) Quantity Availability
25g 20.37
100g 53.25
250g 85.18
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Dimethyl fumarate, 99%

MDL
MFCD00064438
EINECS
210-849-0

Chemical Properties

Formula
C6H8O4
Formula Weight
144.13
Melting point
102-105°
Boiling Point
192-193°
Density
1.37
Solubility
Soluble in water (1.6 mg/ml at 20°C), methanol (30-36 mg/ml), ethanol (10 mg/ml at 25°C), DMSO (29 mg/ml at 25°C), and DMF (~12 mg/ml).

Applications

Dimethyl fumarate acts as an immunomodulator. It is also used in cycloaddition reactions involving ylides, benzenes and amino acids. It is added to food grains,tobacco,leather and preservation. Clothing

Notes

Do not store together with acids. Incompatible with acids, bases, oxidizing agents, reducing agents. Store at room temperature.

Literature References

BW van Oosten; J Killestein; F Barkhof; Chris H. Polman,; Mike P. Wattjes. PML in a Patient Treated with Dimethyl Fumarate from a Compounding Pharmacy. N Engl J Med. 2013, 368 1658-1659.

GHS Hazard and Precautionary Statements

Hazard Statements: H312-H315-H319-H317-H335-H303

Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation. May be harmful if swallowed.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P363-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,4287
Beilstein
774590
Harmonized Tariff Code
2917.19
TSCA
Yes
RTECS
EM6125000

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