Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

485-47-2 - Ninhydrin, 99% - 2,2-Dihydroxy-1,3-indanedione - 1,2,3-Indantrione - A10409 - Alfa Aesar

A10409 Ninhydrin, 99%

CAS Number
485-47-2
Synonyms
2,2-Dihydroxy-1,3-indanedione
1,2,3-Indantrione

Size Price ($) Quantity Availability
10g 16.72
25g 35.43
50g 62.62
250g 267.80
Add to Cart Add to Quote Request View Item

Ninhydrin, 99%

MDL
MFCD00003791
EINECS
207-618-1

Chemical Properties

Formula
C9H6O4
Formula Weight
178.14
Melting point
251° dec.
Sensitivity
Light Sensitive
Solubility
Soluble in water, acetone, ethanol, and methanol. Slightly soluble in chloroform and ether.

Applications

Ninhydrin is used for the determination of amino groups in amino acids, peptides and proteins. It finds application in forensic science for the analysis of latent fingerprints on porous surfaces such as paper. It is also used in thin layer chromatography (TLC) to monitor the progress of chemical reactions. In Kaiser test, it plays an important role to monitor the deprotection in solid phase peptide synthesis.

Notes

Light Sensitive. Incompatible with strong oxidizing agents, amines, alkalis and strong bases.

Literature References

Reagent for the detection and determination of peptides and amino acids.

Reviews: Chem. Rev., 60, 39 (1960); Tetrahedron, 34, 1285 (1978); 47, 8791 (1991).

Babu, K. R.; Khan, F. A. A domino reaction of tetrahalo-7, 7-dimethoxybicyclo [2.2. 1] heptenyl alcohols leading to indenones and a de novo synthesis of ninhydrin derivatives. Org. Biomol. Chem. 2015, 13 (1), 299-308.

Omar, M. A.; Hammad, M. A.; Nagy, D. M.; Aly, A. A. Development of spectrofluorimetric method for determination of certain aminoglycoside drugs in dosage forms and human plasma through condensation with ninhydrin and phenyl acetaldehyde. Spectrochim. Acta, Part A 2015, 136, 1760-1766.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6554
Beilstein
1910963
Harmonized Tariff Code
2914.39
TSCA
Yes
RTECS
NK5425000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware