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Glutaraldehyde is used as a cross linking agent for gelatin, poly(vinyl alcohol) and polyheptapeptides. It is also used as a fixative for electron microscopy and as disinfectants. It provides water resistance to protein and polyhydroxy compounds by reacting through cross linking. It acts as an intermediate for the production of resins, dyestuffs, pharmaceuticals, photographic films and for stabilization of proteins on agarose beads, activation of polystyrene and glass for immobilization of antibodies and antigens and coupling peptides onto carrier proteins.
Woods, A.; Patela, A.; Spina, D.; Riffo-Vasquez, Y.; Babin-Morgan, A.; Rosales, R. T. M.; Sunassee, K.; Clark, S.; Collins, H.; Bruce, K.; Dailey, L. A.; Forbes, B. In vivo biocompatibility, clearance, and biodistribution of albumin vehicles for pulmonary drug delivery. J. Controlled Release 2015, 210, 1-9.
Lu, W.; Ma, M.; Xu, H.; Zhang, B.; Cao, X.; Guo, Y. Gelatin nanofibers prepared by spiral-electrospinning and cross-linked by vapor and liquid-phase glutaraldehyde. Mater. Lett. 2015, 140, 1-4.
Hazard Statements: H301-H314-H317-H330-H334
Toxic if swallowed. Causes severe skin burns and eye damage. May cause an allergic skin reaction. Fatal if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements: P260-P264b-P270-P271-P272-P280-P284-P285-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. Wear respiratory protection. In case of inadequate ventilation wear respiratory protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant