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A10628 Bis(cyclohexanone) oxaldihydrazone, 98%

CAS Number
370-81-0
Synonyms
Oxalic acid bis(cyclohexylidenehydrazide)
Cuprizon I

Stock No. Size Price ($) Quantity Availability
A10628-14 25g 41.10
A10628-22 100g 132.00
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Bis(cyclohexanone) oxaldihydrazone, 98%

MDL
MFCD00001659
EINECS
206-729-2

Chemical Properties

Formula
C14H22N4O2
Formula Weight
278.36
Melting point
208-212°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in alcohol. Insoluble in water.

Applications

Bis(cyclohexanone) oxaldihydrazone is used in the quantitative spectroscopic determination of copper. It is also essential for the experimental study of mitochondrial metabolism. It is used to study the human demyelinating diseases such as multiple sclerosis and components of neuroinflammation. Further, it acts as ligand and catalyzes Ullmann-type C-N bond forming reactions in the presence of copper salt.

Notes

Incompatible with strong oxidizing agents and strong bases.

Literature References

Reagent for spectrophotometric determination of Cu(II): Anal. Chem., 38, 911 (1966).

Krauspe, B. M.; Dreher, W.; Beyer, C.; Baumgartner, W.; Denecke, B.; Janssen, K.; Langhans, C. D.; Clarner, T.; Kipp, M. Short-Term Cuprizone Feeding VerifiesN-Acetylaspartate Quantification as a Marker of Neurodegeneration. J. Mol. Neurosci. 2015, 55 (3), 733-748.

Slowik, A.; Schmidt, T.; Beyer, C.; Amor, S.; Clarner, T.; Kipp, M. The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. Br. J. Pharmacol. 2015, 172 (1), 80-92.

Other References

Beilstein
2388004
Harmonized Tariff Code
2928.00
TSCA
Yes
RTECS
RO2520000

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