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3-Chloropropanesulfonyl Chloride is an intermediate used in the preparation of many enzymatic inhibitors. It is also used in the generation and trapping of the derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids provide chiral sultams and sultones. It is mainly used for the synthesis of pharmaceutical intermediates.
RK Bakshi.; Q Hong.; R Tang.; RN Kalyani. Optimization of a privileged structure leading to potent and selective human melanocortin subtype-4 receptor ligands. span class="italictxt"> Bioorganic & Medicinal Chemistry Letters. 2006 16, (5) , 1130-1133.
C Shah.; L McAtee.; JG Breitenbucher.; D Rudolph. Novel human histamine H 3 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 2002 12, (22) , 3309-3312.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.