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A10721 5-Bromo-2-fluorotoluene, 98+%

CAS Number
51437-00-4
Synonyms

Stock No. Size Price ($) Quantity Availability
A10721-06 5g 36.80
A10721-14 25g 123.00
A10721-22 100g 421.00
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5-Bromo-2-fluorotoluene, 98+%

MDL
MFCD00000343
EINECS
257-202-9

Chemical Properties

Formula
C7H6BrF
Formula Weight
189.03
Boiling Point
94-95°/50mm
Flash Point
73°(163°F)
Density
1.486
Refractive Index
1.5290
Storage & Sensitivity
Ambient temperatures.
Solubility
Not miscible or difficult to mix in water.

Applications

5-Bromo-2-fluorotoluene is used in the preparation of 5-bromo-2-fluorobenzyl bromide via N-bromosuccinimide (NBS) bromination, required for the synthesis of crown bromofluorobenzene and 3-(4-fuoro-3-methylphenyl)acrylamide. It is also used as an intermediates of medicine.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

M. Sletzinger.; T.R. Verhoeven.; R.P. Volante.; J.M. McNamara.; E.G. Corley.; T.M.H. Liu. A diastereospecific, non-racemic synthesis of a novel β-hydroxy-δ-lactone HMG-CoA reductase inhibitor. Tetrahedron Letters. 1985, 26, (25), 2951-2954.

Praew Thansandote.; Eugene Chong.; Kai-Oliver Feldmann.; Mark Lautens. Palladium-Catalyzed Domino C-C/C-N Coupling Using a Norbornene Template: Synthesis of Substituted Benzomorpholines, Phenoxazines, and Dihydrodibenzoxazepines. J. Org. Chem. 2010, 75 (10), 3495-3498.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H315-H319-H335

Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
2242693
Harmonized Tariff Code
2903.99
TSCA
No

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