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336-59-4 - Heptafluorobutyric anhydride, 98% - A10744 - Alfa Aesar

A10744 Heptafluorobutyric anhydride, 98%

CAS Number
336-59-4
Synonyms

Size Price ($) Quantity Availability
5g 31.72
25g 93.32
100g 282.60
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Heptafluorobutyric anhydride, 98%

MDL
MFCD00000432
EINECS
206-410-8

Chemical Properties

Formula
C8F14O3
Formula Weight
410.06
Melting point
-43°
Boiling Point
108-110°
Density
1.662
Refractive Index
1.2870
Sensitivity
Moisture Sensitive
Solubility
Miscible with halogenated solvents. Immiscible with polar solvents.

Applications

Heptafluorobutyric anhydride is used as a derivatization reagent for gas chromatography - mass mass spectrometry analysis of the stereoisomer content of synthetic peptides. It is a GC derivatizing agent used to prepare volatile derivatives of amino acids and other biologically active compounds.

Notes

Incompatible with moist air, water, strong oxidizing agents, strong acids and strong bases.

Literature References

Cappelle, D.; Neels, H.; Yegles, M.; Paulus, J.; van Nuijs, A. L.; Covaci, A.; Crunelle, C. L. Gas chromatographic determination of ethyl glucuronide in hair: Comparison between tandem mass spectrometry and single quadrupole mass spectrometry. Forensic Sci. Int. 2015, 249, 20-24

Nikolaou, P.; Papoutsis, I.; Spiliopoulou, C.; Voudris, C.; Athanaselis, S. A fully validated method for the determination of lacosamide in human plasma using gas chromatography with mass spectrometry: Application for therapeutic drug monitoring. J. Sep. Sci. 2015, 38, (2), 260-266.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2915.90
TSCA
Yes

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