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Heptafluorobutyric anhydride is used as a derivatization reagent for gas chromatography - mass mass spectrometry analysis of the stereoisomer content of synthetic peptides. It is a GC derivatizing agent used to prepare volatile derivatives of amino acids and other biologically active compounds.
Cappelle, D.; Neels, H.; Yegles, M.; Paulus, J.; van Nuijs, A. L.; Covaci, A.; Crunelle, C. L. Gas chromatographic determination of ethyl glucuronide in hair: Comparison between tandem mass spectrometry and single quadrupole mass spectrometry. Forensic Sci. Int. 2015, 249, 20-24
Nikolaou, P.; Papoutsis, I.; Spiliopoulou, C.; Voudris, C.; Athanaselis, S. A fully validated method for the determination of lacosamide in human plasma using gas chromatography with mass spectrometry: Application for therapeutic drug monitoring. J. Sep. Sci. 2015, 38, (2), 260-266.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P201-P280i-P304+P340-P405-P501a
Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.