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501-30-4 - Kojic acid, 99% - 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one - A10760 - Alfa Aesar

A10760 Kojic acid, 99%

CAS Number
501-30-4
Synonyms
5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

Size Price ($) Quantity Availability
5g 40.17
25g 143.10
100g 460.80
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Kojic acid, 99%

MDL
MFCD00006580
EINECS
207-922-4

Chemical Properties

Formula
C6H6O4
Formula Weight
142.11
Melting point
152-155°
Solubility
Soluble in water, acetone (freely soluble), ethanol (freely soluble), methanol, DMSO, ethyl acetate (slightly soluble), chloroform (slightly soluble), pydidine (slightly soluble) and ether (slightly soluble). Insoluble in benzene.

Applications

Kojic acid may be used on cut fruits to prevent oxidative browning, in seafood to preserve pink and red colors and in cosmetics to lighten skin. It is used to treat skin diseases like melasma as it has antibacterial and antifungal properties. It is used as a chelation agent that inhibits melanin production and also as a tyrosine kinase inhibitor.

Notes

Should be stored at room temperature. Stable under recommended storage conditions. Incompatible with oxidizing agents and bases.

Literature References

Juana Cabenes; Soledad Chazarra; Francisco Garcia-Carmona. Kojic acid, a cosmetic Skin whitening agent, is a slow-binding inhibitor of catecholase activity of tyrosinase. Journal of Pharmacy and Pharmacology. 1994, 46, (12),982-985

 

Jon S.Chen; Cheng I.Wei; Marty R.Marshall. Inhibition mechanism of kojic acid on polyphenol oxidase. J. Agric. Food Chem. 1991, 39, (11),1897-1901

GHS Hazard and Precautionary Statements

Hazard Statements: H351

Suspected of causing cancer.

Precautionary Statements: P201-P281-P202-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5317
Beilstein
120895
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
UQ0875000

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