Nitroethane is used as industrial solvents and pharmaceutical intermediates, explosives and as rocket fuel.
David J. T. Porters.; Harold J. Bright. Mechanism of Oxidation of Nitroethane by Glucose Oxidase. The Journal Of Biological Chemistry. 1977, 252, (12), 4361-4370.
Syun-ichi Kiyooka.; Yuichi Kaneko.; Ken-ichi Kume. The catalytic asymmetric aldol reaction of silyl ketene acetals with aldehydes in the presence of a chiral borane complex. Nitroethane as a highly effective solvent for catalytic conditions. Tetrahedron Letters. 1992, 33, (34), 4927-4930.
Aldehydes are converted to nitriles in one step in the presence of NaOAc/AcOH (NH4OAc gives the "expected" alkylidene derivative): Synthesis, 510 (1985):
For a review of the use of nitro-compounds as alkyl anion synthons, including methods for removing the nitro-group from the resulting carbon skeletons, see: Synthesis, 833 (1988).
For further reactions of aliphatic nitro-compounds, see Nitromethane, A11806.
Hazard Statements: H226-H302-H332
Flammable liquid and vapour. Harmful if swallowed. Harmful if inhaled.
Precautionary Statements: P210-P261-P280a-P303+P361+P353-P304+P340-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Dispose of contents/container in accordance with local/regional/national/international regulations.