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2,3,5-Triphenyl-2H-tetrazolium chloride is used as a redox indicator. It is also used in biochemical experiments, especially to indicate cellular respiration. It is employed in autopsy pathology to assist identification of post-mortem myocardial infarctions.
Reagent for detection of reducing sugars.
Oxidizing agent, reduced to the colored formazan, capable of introducing a -hydroxyl substituent into steroidal enones: J. Chem. Soc., Perkin 1, 2687 (1988).
McLaughlin, M. R.; Balaa, M. F. Enhanced contrast of bacteriophage plaques in Salmonella with ferric ammonium citrate and sodium thiosulfate (FACST) and tetrazolium red (TZR). J. Microbiol. Methods 2006, 65 (2), 318-323.
Li, X.; Deng, S.; Fu, H. Synergism between red tetrazolium and uracil on the corrosion of cold rolled steel in H2SO4 solution. Corros. Sci. 2009, 51 (6), 1344-1355.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant