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A10891 Benzenesulfonamide, 98+%

CAS Number
98-10-2
Synonyms

Stock No. Size Price ($) Quantity Availability
A10891-30 250g 36.60
A10891-0B 1000g 105.00
A10891-0I 5000g 398.00
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Benzenesulfonamide, 98+%

MDL
MFCD00007930
EINECS
202-637-1

Chemical Properties

Formula
C6H7NO2S
Formula Weight
157.19
Melting point
151-154°
Flash Point
250°(482°F)
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in methanol (25 mg/ml), and water (4.3 mg/ml at 16°C).

Applications

Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. Biospecific binding of carbonic anhydrase to mixed sams presenting benzenesulfonamide ligands led to a model system for studying lateral steric effects. Benzenesulfonamide modifications at c-7 of ciprofloxacin change its primary target instreptococcus pneumoniae from topoisomerase iv to gyrase. Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Milan Mrksich,; Jocelyn R. Grunwell,; George M. Whitesides .Biospecific Adsorption of Carbonic Anhydrase to Self-Assembled Monolayers of Alkanethiolates That Present Benzenesulfonamide Groups on Gold. J. Am. Chem. Soc., . 1995, 117 (48),12009-12010.

Joydeep Lahiri,; Lyle Isaacs,; Bartosz Grzybowski,; Jeffrey D. Carbeck,; George M. Whitesides. title . Langmuir. 1999, 15(21),7186-7198.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264b-P270-P301+P312-P330-P501c

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1100566
Harmonized Tariff Code
2935.90
TSCA
Yes
RTECS
DA9380000

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