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Barbituric acid is widely used in the manufacturing of plastics, textiles, polymers and pharmaceuticals. It is an active ingredient in the production of Vitamin B2. It is a strong acid in an aqueous medium with an active methylene group involved Knoevenegal condensation. It is used as precursor for the preparation of 5-arylidene barbituric acid by reacting with aromatic aldehyde. It is also used in electrochemical oxidation of iodine using cyclic voltammetry and controlled potential coulometry.
Zhou, K.; Fu, H.; Feng, L.; Cui, M.; Dai, J.; Liu, B. The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques. Chem. Commun. 2015, 51 (58), 11665-11668.
Qin, J.; Wang, S.; Ren, H.; Hou, Y.; Wang, X. Photocatalytic reduction of CO2 by graphitic carbon nitride polymers derived from urea and barbituric acid. Appl. Catal., B 2015, 179, 1-8.