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22572-40-3 - 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide methiodide, 98% - N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide methiodide - A10962 - Alfa Aesar

A10962 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide methiodide, 98%

CAS Number
22572-40-3
Synonyms
N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide methiodide

Size Price ($) Quantity Availability
1g 19.38
5g 60.87
25g 227.70
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1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide methiodide, 98%

MDL
MFCD00011833
EINECS
245-095-1

Chemical Properties

Formula
CH3CH2N=C=N(CH2)3N(CH3)3I
Formula Weight
297.17
Melting point
90-92°
Sensitivity
Light Sensitive & Hygroscopic
Solubility
Soluble in water.

Applications

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide methiodide is in proteins as water soluble carboxyl modifying reagent. It is used as a crosslinking agent.

Notes

Keep in a dry, cool and well-ventilated place. Keep container tightly closed. Incompatible with acids, strong oxidizing agents, moist air and water.

Literature References

Peptide coupling reagent: both the reagent and the urea by-product are soluble in neutral aqueous media.

/n

Jiang, J.; Yang, E.; Reddy, K. R.; Niedzwiedzki, D. M.; Kirmaier, C.; Bocian, D. F.; Holten, D.; Lindsey, J. S. Synthetic bacteriochlorins bearing polar motifs (carboxylate, phosphonate, ammonium and a short PEG). Water-solubilization, bioconjugation, and photophysical properties. New J. Chem. 2015, 39, 5694-5714.

Ren, T.; Liu, Q.; Lu, H.; Liu, H.; Zhang, X.; Du, J. Multifunctional polymer vesicles for ultrasensitive magnetic resonance imaging and drug delivery. J. Mater. Chem. 2012, 22, 12329-12338.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
4162760
Harmonized Tariff Code
2925.19
TSCA
No

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