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Acetic hydrazide is used as an antibiotic for the treatment of mycobacterium tuberculosis. It is also involved in the preparation of sunitinib b reacting with 5-fluoroisatin. Further, it inhibits mycolic acid biosynthesis. It serves as an important intermediate in organic synthesis such as nitric furosemide Long (nifuratrone) in medicine.
Sadhukhan, D.; Maiti, M.; Pilet, G.; Bauzá, A.; Frontera, A.; Mitra, S. Hydrogen Bond, pi-pi, and CH-pi Interactions Governing the Supramolecular Assembly of Some Hydrazone Ligands and Their MnII Complexes - Structural and Theoretical Interpretation. Eur. J. Inorg. Chem. 2015, 2015 (11), 1958-1972.
Sadhukhan, D.; Maiti, M.; Zangrando, E.; Pathan, S.; Mitra, S.; Patel, A. Heterogeneous catalytic oxidation of styrene by an oxo bridged divanadium(V) complex of an acetohydrazide-Schiff base. Polyhedron 2014, 69, 1-9.
Hazard Statements: H228-H302-H315-H319-H332-H335
Flammable solid. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Harmful if inhaled. May cause respiratory irritation.
Precautionary Statements: P210-P240-P241-P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant