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The compound is a prolyl 4-hydroxylase inhibitor and can be used to protect the myocardium.
Bianca L. Garner.; Jean E.L. Arceneaux.; Rowe Byers, B. Temperature Control of a 3,4-Dihydroxybenzoate (Protocatechuate)-Based Siderophore in Bacillus anthracis. Current Microbiology. 2000, 49, (2), 89-94.
Osamu Saitoh.; Muthu Periasamy.; Mikio Kan.; Ryoichi Matsuda. Cis-4-hydroxy-l-proline and ethyl-3,4-dihydroxybenzoate prevent myogenesis of C2C12 muscle cells and block myoD1 and myogenin expression. Experimental Cell Research. 1992, 200, (1), 70-76.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant