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A11018 3-Nitro-L-tyrosine, 98%

CAS Number
621-44-3
Synonyms
H-3-Nitro-Tyr-OH

Stock No. Size Price ($) Quantity Availability
A11018-06 5g 34.90
A11018-14 25g 135.00
A11018-22 100g 459.00
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3-Nitro-L-tyrosine, 98%

MDL
MFCD00007123
EINECS
210-688-6

Chemical Properties

Formula
C9H10N2O5
Formula Weight
226.19
Melting point
ca 230° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water (partly miscible), 1N hydrochloric acid (50 mg/ml), acidic aqueous solution , ethanol, DMSO, DMF and PBS (pH 7.2) (~2 mg/ml).

Applications

3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Wakako Maruyamaa; Yoshio Hashizumeb; Kazuo Matsubarac; Makoto Naoi. Identification of 3-nitro-l-tyrosine, a product of nitric oxide and superoxide, as an indicator of oxidative stress in the human brain. Journal of Chromatography B: Biomedical Sciences and Applications. 1996, 676,(1), 153-158.

 

Mohammad A.Tabrizi-Fard; Tristan S.Maurer; Ho-Leung Fung. In vivo disposition of 3-nitro-l-tyrosine in rats: Implications on tracking systemic peroxynitrite exposure. Drug Metabolism & Disposition. 1999, 27,(4), 429-431.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
2813157
Harmonized Tariff Code
2922.50
TSCA
No

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