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156-54-7 - Sodium butyrate, 98+% - Butyric acid sodium salt - A11079 - Alfa Aesar

A11079 Sodium butyrate, 98+%

CAS Number
156-54-7
Synonyms
Butyric acid sodium salt

Size Price ($) Quantity Availability
5g 17.20
100g 29.49
500g 93.70
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Sodium butyrate, 98+%

MDL
MFCD00002816
EINECS
205-857-6

Chemical Properties

Formula
C4H7NaO2
Formula Weight
110.09
Melting point
>300°
Sensitivity
Hygroscopic
Solubility
Soluble in water, dimethyl sulfoxide and ethanol. Insoluble in ether.

Applications

Decreases calcium release from intracellular stores. Inhibits histone deacetylase.Sodium butyrate is used in the treatment of human spinal muscular atrophy patients. Further, it is used in the determination of the role of histone acetylation in chromatin structure and function.

Notes

Incompatible with strong oxidizing agents.

Literature References

Cavini, S.; Iraira, S.; Siurana, A.; Foskolos, A.; Ferret, A.; Calsamiglia, S. Effect of sodium butyrate administered in the concentrate on rumen development and productive performance of lambs in intensive production system during the suckling and the fattening periods. Small Rumin. Res. 2015, 123 (2-3), 212-217.

Xu, H.; McCoy, A.; Li, J.; Zhao, Y.; Ghishan, F. K. Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. Am. J. Physiol. Gastrointest. Liver Physiol. 2015, 309 (6), G500-G505.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3629439
Harmonized Tariff Code
2915.60
TSCA
Yes
RTECS
ET6400000

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