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A11079 Sodium butyrate, 98+%

CAS Number
156-54-7
Synonyms
Butyric acid sodium salt

Stock No. Size Price ($) Quantity Availability
A11079-06 5g 19.00
A11079-22 100g 30.70
A11079-36 500g 102.00
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Sodium butyrate, 98+%

MDL
MFCD00002816
EINECS
205-857-6

Chemical Properties

Formula
C4H7NaO2
Formula Weight
110.09
Melting point
>300°
Storage & Sensitivity
Hygroscopic. Ambient temperatures.
Solubility
Soluble in water, dimethyl sulfoxide and ethanol. Insoluble in ether.

Applications

Decreases calcium release from intracellular stores. Inhibits histone deacetylase.Sodium butyrate is used in the treatment of human spinal muscular atrophy patients. Further, it is used in the determination of the role of histone acetylation in chromatin structure and function.

Notes

Incompatible with strong oxidizing agents.

Literature References

Cavini, S.; Iraira, S.; Siurana, A.; Foskolos, A.; Ferret, A.; Calsamiglia, S. Effect of sodium butyrate administered in the concentrate on rumen development and productive performance of lambs in intensive production system during the suckling and the fattening periods. Small Rumin. Res. 2015, 123 (2-3), 212-217.

Xu, H.; McCoy, A.; Li, J.; Zhao, Y.; Ghishan, F. K. Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. Am. J. Physiol. Gastrointest. Liver Physiol. 2015, 309 (6), G500-G505.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3629439
Harmonized Tariff Code
2915.60
TSCA
Yes
RTECS
ET6400000

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