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A11137 5-Chloro-8-hydroxy-7-iodoquinoline, 98%

CAS Number
130-26-7
Synonyms
Clioqinol

Stock No. Size Price ($) Quantity Availability
A11137-09 10g 34.90
A11137-18 50g 119.00
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5-Chloro-8-hydroxy-7-iodoquinoline, 98%

MDL
MFCD00006787
EINECS
204-984-4

Chemical Properties

Formula
C9H5ClINO
Formula Weight
305.49
Melting point
ca 175° dec.
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in DMSO (>25 mg/ml), boiling alcohol ((1:43)), methanol, and chloroform ((1:120)).

Applications

Clioquinol is a metal chelating ligand which displays protective effects in various neurodegenerative states as well as being a component in antifungal and antiprotozoal agents. Clioquinol rescues lead-induced impairments of synaptic plasticity in an animal models

Notes

Keep container tightly closed. Store away from oxidizing agents.

Literature References

Yogendu Sharma. A sensitive spectrophotometric determination of niobium(V) with the reagent 5-chloro-8-hydroxy-7-iodoquinoline. Microchimica Acta. 1982, 78, (3-4), 297-303.

Markus Albrecht.; Marcel Fiege.; Olga Osetska. 8-Hydroxyquinolines in metallosupramolecular chemistry. Coordination Chemistry Reviews. 2008, 252, (8-9), 812-824.

GHS Hazard and Precautionary Statements

Hazard Statements: H317-H334-H361

May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Suspected of damaging fertility or the unborn child.

Precautionary Statements: P201-P202-P261-P272-P280g-P281-P285-P302+P352-P304+P341-P308+P313-P333+P313-P342+P311-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. Use personal protective equipment as required. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. If skin irritation or rash occurs: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,5031
Beilstein
153637
Harmonized Tariff Code
2933.49
TSCA
Yes
RTECS
VC5075000

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