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4774-14-5 - 2,6-Dichloropyrazine, 98% - A11175 - Alfa Aesar

A11175 2,6-Dichloropyrazine, 98%

CAS Number
4774-14-5
Synonyms

Size Price ($) Quantity Availability
5g 122.40
25g 364.80
100g 1271.20
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2,6-Dichloropyrazine, 98%

MDL
MFCD00006125
EINECS
225-316-8

Chemical Properties

Formula
C4H2Cl2N2
Formula Weight
148.98
Melting point
52-56°
Flash Point
>110°(230°F)
Solubility
Soluble in ethanol and methanol.

Applications

2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. It is also used in the synthesis of oxacalixarenes containing nitrogen heterocycles.

Notes

Store in a cool place. Incompatible with strong oxidizing agents and strong acids and bases.

Literature References

Zhao, M.; Li, P.; Xie, X.; Su, J.; Zheng, W. Synthesis and structural characterization of 2,6-bis(1,2,4-diazaphospholyl-1-yl)pyridine zinc and 2,6-bis(1,2,4-diazaphospholyl-1-yl)pyrazine copper complexes. Polyhedron 2015, 85, 302-311.

Tominaga, M.; Kunitomi, N.; Katagiri, K.; Itoh, T. Adamantane-Based Oxacyclophanes Containing Pyrazines: Synthesis, Crystal Structure, and Self-Assembly Behavior. Org. Lett. 2015, 17 (4), 786-789.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2439
Harmonized Tariff Code
2933.99
TSCA
Yes

Recommended

  • A10974

    Pyrazine-2-carbonitrile, 97+%
  • A11076

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  • 11847

    Phosphorus(V) oxychloride, 99.999% (metals basis)

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