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A11175 2,6-Dichloropyrazine, 98%

CAS Number
4774-14-5
Synonyms

Stock No. Size Price ($) Quantity Availability
A11175-06 5g 125.00
A11175-14 25g 383.00
A11175-22 100g 1459.00
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2,6-Dichloropyrazine, 98%

MDL
MFCD00006125
EINECS
225-316-8

Chemical Properties

Formula
C4H2Cl2N2
Formula Weight
148.98
Melting point
52-56°
Flash Point
>110°(230°F)
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in ethanol and methanol.

Applications

2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. It is also used in the synthesis of oxacalixarenes containing nitrogen heterocycles.

Notes

Store in a cool place. Incompatible with strong oxidizing agents and strong acids and bases.

Literature References

Zhao, M.; Li, P.; Xie, X.; Su, J.; Zheng, W. Synthesis and structural characterization of 2,6-bis(1,2,4-diazaphospholyl-1-yl)pyridine zinc and 2,6-bis(1,2,4-diazaphospholyl-1-yl)pyrazine copper complexes. Polyhedron 2015, 85, 302-311.

Tominaga, M.; Kunitomi, N.; Katagiri, K.; Itoh, T. Adamantane-Based Oxacyclophanes Containing Pyrazines: Synthesis, Crystal Structure, and Self-Assembly Behavior. Org. Lett. 2015, 17 (4), 786-789.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
2439
Harmonized Tariff Code
2933.99
TSCA
Yes

Recommended

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    Pyrazine-2-carbonitrile, 97+%
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