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3,4-dihydroxy-L-phenylalanine (DOPA) is used as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells. It is also used as an anticholinergic drug and used in the treatment of Parkinson's disease. It acts as an intermediate in the biosynthesis of other catecholamines (norepinephrine, epinephrine) and melanin. It acts as a precursor of dopamine product of tyrosine hydroxylase.
Fichman, G.; Adler-Abramovich, L.; Manohar, S.; Mironi-Harpaz, I.; Guterman, T.; Seliktar, D.; Messersmith, P. B.; Gazit, E. Seamless Metallic Coating and Surface Adhesion of Self-Assembled Bioinspired Nanostructures Based on Di-(3,4-dihydroxy-l-phenylalanine) Peptide Motif. ACS Nano. 2014, 8 (7), 7220-7228.
Huang, Y.; Han, Q.; Zhang, Q.; Guo, L.; Guo, D.; Yingzi Fu, Y. A fast chiral sensing to DOPA enantiomers via poly-lysine films matrixes. Electrochim. Acta. 2013, 113, 564-569.
Yue, Q.; Wang, M.; Sun, Z.; Wang, C.; Wang, C.; Deng, Y.; Zhao, D. A versatile ethanol-mediated polymerization of dopamine for efficient surface modification and the construction of functional core-shell nanostructures.
Xiong, S.; Wang, Y.; Zhu, J.; Yu, J.; Hu, Z. Mussel-Adhesive-Inspired Fabrication of Multifunctional Silver Nanoparticle Assemblies. Langmuir 2015, 31 (19), 5504-5512.
Matin, M. A.; Chitumalla, R. K.; Lim, M.; Gao, X.; Jang, J. Density Functional Theory Study on the Cross-Linking of Mussel Adhesive Proteins. J. Phys. Chem. B 2015, 119 (17), 5496-5504.
Hazard Statements: H302
Harmful if swallowed.
Precautionary Statements: P264b-P270-P301+P312-P330-P501c
Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant