Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

56-05-3 - 2-Amino-4,6-dichloropyrimidine, 98% - 4,6-Dichloro-2-pyrimidinamine - A11330 - Alfa Aesar

A11330 2-Amino-4,6-dichloropyrimidine, 98%

CAS Number
56-05-3
Synonyms
4,6-Dichloro-2-pyrimidinamine

Size Price ($) Quantity Availability
5g 43.67
25g 138.02
100g 436.72
Add to Cart Add to Quote Request View Item

2-Amino-4,6-dichloropyrimidine, 98%

MDL
MFCD00006090
EINECS
200-253-9

Chemical Properties

Formula
C4H3Cl2N3
Formula Weight
164.00
Melting point
218-222°
Solubility
Insoluble in water, soluble in acetone, two monomer (VCM) and thermal toluene.

Applications

Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Dana Hocková,; Antonı?n Holý,; Milena Masojı?dková,; Ivan Votruba. An efficient synthesis of cytostatic mono and bis-alkynylpyrimidine derivatives by the Sonogashira cross-coupling reactions of 2,4-diamino-6-iodopyrimidine and 2-amino-4,6-dichloropyrimidine. Tetrahedron. 2004, 60 (23), 4983-4987.

C. J. B. Clews,; W. Cochran. The structures of pyrimidines and purines. I. A determination of the structures of 2-amino-4-methyl-6-chloropyrimidine and 2-amino-4,6-dichloropyrimidine by X-ray methods . Acta Cryst.. 1948, 14-11.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
118454
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
UV6260485

Recommended

  • A15540

    Nickel(II) nitrate hexahydrate, 98%
  • A16549

    Platinum(II) chloride, 98%
  • B22797

    4-Amino-2,2-difluoro-1,3-benzodioxole, 97+%
  • L18575

    2-Cyanoethyl diisopropylchlorophosphoramidite, 95%
  • H55007

    2-Amino-4-chloropyrimidine, 98%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware