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Pentadecanolide is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen. Pentadecanolide may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization. It may be employed as starting reagent for the synthesis of terminally-branched iso-fatty acids (iso-C15-C17).
Wilberth H-K, et al. Effect of reaction temperature on the physicochemical properties of poly (pentadecanolide) obtained by enzyme-catalyzed ring-opening polymerization. . Polymer Bull. 2015, 72(3), 1-12.
Mark B Richardson,; Spencer J Williams. A practical synthesis of long-chain iso-fatty acids (iso-C12-C19) and related natural products. . Beilstein Journal of Organic Chemistry. 2013, 9 1807-1812 .
Hazard Statements: H317
May cause an allergic skin reaction.
Precautionary Statements: P261-P272-P280g-P302+P352-P333+P313-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant