In order to establish defined biomacromolecular systems for mineralised tissue applications, type I collagen was functionalised with 1,3-phenylenediacetic acid (Ph) and investigated at the molecular, macroscopic and functional levels. The solvothermal reactions of 1,2-bis(imidazol-1?-yl)ethane (bime), 1,3-phenylenediacetic acid, 1,4-phenylenediacetic acid), 1,2-phenylenediacetic acid with different metal ions gave rise to four novel helical coordination polymers.
Halil Gökce,; Semiha Bahçeli. Quantum chemical computations of 1,3-phenylenediacetic acid . Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2011, 78 (2),803-808.
Giuseppe Tronci,; Amanda Doyle,; Stephen J. Russell,; David J. Wood. Triple-helical collagen hydrogels via covalent aromatic functionalisation with 1,3-phenylenediacetic acid. J. Mater. Chem. B. 2013, 1 issue , 5478-5488.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P280g-P305+P351+P338
Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.