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52-67-5 - D-(-)-Penicillamine, 99% - 3,3-Dimethyl-D-cysteine - 3-Mercapto-D-valine - A11446 - Alfa Aesar

A11446 D-(-)-Penicillamine, 99%

CAS Number
52-67-5
Synonyms
3,3-Dimethyl-D-cysteine
3-Mercapto-D-valine

Size Price ($) Quantity Availability
5g 48.41
25g 188.49
100g 558.00
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D-(-)-Penicillamine, 99%

MDL
MFCD00064302
EINECS
200-148-8

Chemical Properties

Formula
C5H11NO2S
Formula Weight
149.21
Melting point
202-204° dec.
Solubility
It is freely soluble in water, slightly soluble in alcohol, insoluble in chloroform, ether, acetone, benzene, and in carbon tetrachloride.

Applications

It is used mainly as chelating agent in heavy metal poisoning as in lead, mercury and copper poisoning. It is used in Wilson's disease. It  is used in pharmacy as chelating agent and as immunosuppressant for treating rheumatoid arthritis by reducing the number of T cells, inhibiting the macrophages, by reducing the activity of "Interleukin 1 and rheumatoid factor and in preventing crosslinking of the collagen. It acts as an exogenous NOS modulator.

Notes

Stable under normal conditions. Incompatabile to strong oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C.

Literature References

Henri Brunner.; Richard Becker.; Georg Riepl. Asymmetric syntheses. 20. Enantioselective hydrosilylation of ketones with [Rh(cod)Cl]2/thiazolidine catalysts. Organometallics.19843, (9), 1354-1359.

Joseph Wang.; Teresa Golden.; Kurian Varughese.; Ibrahim El-Rayes. Polishable and robust modified graphite epoxy electrodes. Anal. Chem.198961, (5), 508-512.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Merck
14,7088
Beilstein
1722375
Harmonized Tariff Code
2930.90
TSCA
No
RTECS
YV9425000

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