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Carbazole and its derivatives are widely used as an intermediate in synthesis of pharmaceuticals, agrochemicals, dyes, pigments and other organic compounds. carbazole is also used in luminescence chemistry as a photosensitizing and additional charge transport material. Carbazole structure is a motif in pharmaceuticals such as carvedilol used to treat high blood pressure and to prevent cardiac arrhythmias and angina.
Bjorn Akermark.; Lennart Eberson.; Ernst Jonsson.; Egon Pettersson. Palladium-promoted cyclization of diphenyl ether, diphenylamine, and related compounds. J. Org. Chem.197540, (9), 1365-1367.
Frederick G. Bordwell.; George E. Drucker.; Herbert E. Fried. Acidities of carbon and nitrogen acids: the aromaticity of the cyclopentadienyl anion. J. Org. Chem.198146, (3), 632-635.
Hazard Statements: H315-H319-H335-H351
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Suspected of causing cancer.
Precautionary Statements: P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P337+P313-P362-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant